In the present paper we provide a mathematical model that describe the hypothalamus-pituitary-thyroid axis in autoimmune (Hashimoto's) thyroiditis. Since there is a spatial separation between thyroid and pituitary gland in the body, time is needed for transportation of thyrotropin and thyroxine between the glands. Thus, the distributed time delays are considered as both weak and Dirac kernels. The delayed model is analyzed regarding the stability and bifurcation behavior. The last part contains some numerical simulations to illustrate the effectiveness of our results and conclusions.


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    Title :

    Mathematical model describing the thyroids-pituitary axis with distributed time delays in hormone transportation


    Contributors:

    Conference:

    10TH INTERNATIONAL CONFERENCE ON MATHEMATICAL PROBLEMS IN ENGINEERING, AEROSPACE AND SCIENCES: ICNPAA 2014 ; 2014 ; Narvik, Norway


    Published in:

    AIP Conference Proceedings ; 1637 , 1 ; 724-733


    Publication date :

    2014-12-10


    Size :

    10 pages





    Type of media :

    Conference paper


    Type of material :

    Electronic Resource


    Language :

    English




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