Abstract A model is proposed for the early evolution of the coding mechanism. A primordial RNA embodies the functions of today's nucleic acids in a single molecule. The molecule is generated by successive rounds of self-priming and-templating. After proximity is assured by enclosure in a cell, the functions can be partitioned among more efficient specializel molecules. The prediction of sequence homologies in later forms prompted a search for matches between t- and r-RNAs. These are described. Their distributions offer clues to their origins. The existance of overlapping homologies indicates an approach to the reconstruction of an ancestral molecule.
tRNA-rRNA sequence homologies: A model for the origin of a common ancestral molecule, and prospects for its reconstruction
Origins of life ; 14 , 1-4
1984
Article (Journal)
English
Local classification TIB: | 535/3908/4290 | |
BKL: | 44.71 Verkehrsmedizin |
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