Abstract Glycine reacts with heating on dried clays and other minerals to give peptides in much better yield than in the absence of mineral. This reaction was proposed to occur by way of an activated intermediate such as an acyl silicate or acyl aluminate (i.e., the anhydride of a carboxylic acid with Si−OH or Al−OH), analogous to acyl phosphates involved in several biochemical reactions including peptide bond synthesis. We confirmed the proposed mechanism by trapping the intermediate, as well as by direct spectroscopic observation of a related intermediate. The reaction of amino acids on periodically dried mineral surfaces represents a widespread, geologically realistic setting for prebiotic peptide formation viain situ activation.


    Access

    Access via TIB

    Check availability in my library

    Order at Subito €


    Export, share and cite



    Title :

    Acyl silicates and acyl aluminates as activated intermediates in peptide formation on clays


    Contributors:

    Published in:

    Publication date :

    1984




    Type of media :

    Article (Journal)


    Type of material :

    Print


    Language :

    English



    Classification :

    Local classification TIB:    535/3908/4290
    BKL:    44.71 Verkehrsmedizin



    Water-Soluble N-(n-Fatty acyl)chitosans

    Hirano, S. / Yamaguchi, Y. / Kamiya, M. | British Library Online Contents | 2003


    POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING ACYL GROUP

    LUO STEVEN | European Patent Office | 2016

    Free access

    POLYMERS FUNCTIONALISED WITH OXIME COMPOUNDS CONTAINING ACYL GROUP

    LUO STIVEN | European Patent Office | 2016

    Free access

    Clays as possible catalysts for peptide formation in the prebiotic era

    Paecht-Horowitz, Mella | Online Contents | 1976


    Investigation of molten aluminates under containerless conditions

    Weber, R. / Tangeman, J. / Key, T. et al. | AIAA | 2002