Described herein are FasL-engineered biomaterials, as well as methods of making and using such FasL-engineered biomaterials, such as for immunomodulation, such as for inducing immunosuppression and specific immune tolerance, such as for preventing or reducing the risks of rejection of cellular or tissue grafts and/or the treatment of autoimmune disorders such as Type I diabetes. In specific embodiments, the FasL-engineered biomaterials are biotinylated microgels bound to SA-FasL.


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    Title :

    FASL-ENGINEERED BIOMATERIALS WITH IMMUNOMODULATORY FUNCTION


    Contributors:
    SHIRWAN HAVAL (author) / GARCIA ANDRES J (author) / YOLCU ESMA S (author) / ZHAO HONG (author) / HEADEN DEVON (author)

    Publication date :

    2020-02-13


    Type of media :

    Patent


    Type of material :

    Electronic Resource


    Language :

    English


    Classification :

    IPC:    A61K Zubereitungen für medizinische, zahnärztliche oder kosmetische Zwecke , PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES / A61P SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS , Spezifische therapeutische Aktivität von chemischen Verbindungen oder medizinischen Zubereitungen / B60L PROPULSION OF ELECTRICALLY-PROPELLED VEHICLES , Antrieb von elektrisch angetriebenen Fahrzeugen / C12N Mikroorganismen oder Enzyme , MICROORGANISMS OR ENZYMES



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