Abstract The cell culture of a Chinese hamster was irradiated on a Serpuchov proton synchrotron at a dose of 0.5–4 Gy and a dose rate of 1 Gy/min and by gamma-irradiation at dose 1–5 Gy and dose rate 1.2–1.4 Gy/min. The effect of radiation on the cell culture was judged from chromosomal aberrations in G2-stage of cell cycle and micronuclear test. The relative biological efficience of the secondary radiation was approximately 3. Modifying effect of caffeine on the cells irradiated by secondary radiation of synchrotron was not observed. In the presence of caffeine the effect of γ-irradiation practically is increased up to the level observed upon secondary irradiation. This suggests that secondary radiation inhibits the repair of the cytogenetic damage.


    Access

    Check access

    Check availability in my library

    Order at Subito €


    Export, share and cite



    Title :

    Analysis of cytogenetic effects of the secondary radiation resulting from 70 GeV protons of chinese hamster cells


    Contributors:

    Published in:

    Advances in Space Research ; 4 , 10 ; 227-230


    Publication date :

    1984-01-01


    Size :

    4 pages




    Type of media :

    Article (Journal)


    Type of material :

    Electronic Resource


    Language :

    English




    Fragile Sites and Telomeric Sequences in Chinese Hamster Cells

    Musio, A. / Rainaldi, G. / Sbrana, I. et al. | British Library Conference Proceedings | 1995


    Effect of secondary radiation produced by 70 GeV protons on DNA of mammalian cells

    Leont'eva, G.A. / Fomenko, B.S. / Antipov, A.V. | Elsevier | 1984


    Radiation Effects of Protons and Electrons on Backfield Silicon Solar Cells

    Yiyong Wu / Zhengyu Hu / Jingdong Xiao et al. | AIAA | 2006


    Radiation Effects of Protons and Electrons on Backfield Silicon Solar Cells

    Hu, Z. / He, S. / Yang, D. | British Library Conference Proceedings | 2006