The development of novel, multifunctional wound dressings is essential in the goal of achieving new therapies able to increase the quality of the treatment of patients suffering from insufficient wound healing, especially in the case of chronic and infected wounds. Based on the high social, economic and personal impact of skin wounds, ideal wound dressings able to actively protect the wounded skin and promote the healing process are in demand. Among other properties, modern wound dressings should be easy to produce (cost-effective) and should combine antibacterial with angiogenic properties in addition of being mechanically robust and pliable for easy application. Wound dressings, which can be used to deliver topically drugs or molecules, are of great interest as they can face the challenges leading to an effective wound healing process. Bioactive glasses (BGs) are a class of non-crystalline, inorganic materials able to release biologically active ions during implantation in the human body, which can induce specific cell responses such as accelerating haemostasis and angiogenesis. Research on BGs has mainly focused on their use in the field of bone replacing devices and bone tissue engineering. However, an increasing amount of studies is reporting promising results on the use of BGs in the regeneration of soft tissues and in wound healing. By designing new BG compositions with the capability to release ions that induce specific biological reactions, the applications of BGs are being further expanded in soft tissue repair. In this context, BGs have shown great potential for wound healing applications especially when BG compositions incorporating biologically active ions have been considered. Therefore, in the first part of this study, copper and/or zinc containing borosilicate and borate BGs were designed for wound healing applications. Copper was chosen to impart angiogenic properties and zinc to introduce antibacterial effects. The fabricated BGs were chemically and physically characterized and they showed ...


    Zugriff

    Download


    Exportieren, teilen und zitieren



    Titel :

    Development of multifunctional wound dressings by using newly designed ion doped borosilicate and borate bioactive glasses ; Entwicklung multifunktionaler Wundauflagen unter Verwendung neu gestalteter ionendotierter bioaktiver Borosilikat- und Boratgläser


    Beteiligte:

    Erscheinungsdatum :

    01.01.2020


    Medientyp :

    Hochschulschrift


    Format :

    Elektronische Ressource


    Sprache :

    Englisch


    Schlagwörter :

    Klassifikation :

    DDC:    629




    Bioactive glass-based fibrous wound dressings

    Homaeigohar, Shahin / Li, Meng / Boccaccini, Aldo R. | BASE | 2022

    Freier Zugriff


    Multifunktionaler Handhabungsroboter

    YAN KANG / MEI HAIQING | Europäisches Patentamt | 2025

    Freier Zugriff

    Multifunktionaler Laserbearbeitungskopf

    Petring, Dirk / Dickler, Harald | Tema Archiv | 2007


    Multifunktionaler Schiffskran

    PASZKIEWICZ TOMASZ | Europäisches Patentamt | 2016

    Freier Zugriff