Abstract This paper considers human reliability analysis (HRA) for long-duration space missions. HRA has previously been used in the space program to support ground-based operations, Space Shuttle and International Space Station missions. New missions, such as a prospective mission to Mars, present new contexts for human spaceflight, including longer distances and durations, and different gravity levels. For HRA to be used to inform and prevent hazards, new research and data gathering are needed to understand the psychological and physiological aspects of astronautics. This paper outlines several areas of research that would support HRA for long-duration spaceflight. HRA methods must be adapted for space, which requires new data to inform and validate human error categorization and quantification.


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