This poster presentation reviews a study that is designed to address immune system dysregulation and the risk to crewmembers in long duration exploration class missions. This study will address these objectives: (1) Determine the status of adaptive immunity physiological stress, viral immunity, latent herpesvirus reactivation in astronauts during 6 month missions to the International Space Station; (2) determine the clinical risk related to immune dysregulation for exploration class spaceflight; and (3) determine an appropriate monitoring strategy for spaceflight-associated immune dysfunction that could be used for the evaluation of countermeasures. The study anticipates 17 subjects, and for this presentation, (midpoint study data) 10 subjects are reviewed.


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    Title :

    Immune System Dysregulation and Herpesvirus Reactivation Persist During Long-Duration Spaceflight


    Contributors:
    Crucian, B. E. (author) / Mehta, S. (author) / Stowe, R. P. (author) / Uchakin, P. (author) / Quiriarte, H. (author) / Pierson, D. (author) / Sams, C. F. (author)

    Conference:

    18th IAA Humans in Space Symposium ; 2011 ; Houston, TX, United States


    Publication date :

    2011-04-11


    Type of media :

    Miscellaneous


    Type of material :

    No indication


    Language :

    English