Monocyte cell numbers and functions, including phagocytosis, oxidative burst capacity, and degranulation and expression of related surface molecules, were studied in blood specimens from 25 astronauts and 9 healthy control subjects. Blood samples were obtained 10 days before a space flight, 3 hours after landing and 3 days after landing. The number of monocytes in astronauts did not change significantly among the three sample collection periods. Following space flight, the monocytes ability to phagocytize Escherichia coli, to exhibit an oxidative burst, and to degranulate was reduced as compared to monocytes from control subjects. These alterations in monocyte functions after space flight correlated with alterations in the expression of CD32 and CD64.


    Access

    Access via TIB

    Check availability in my library


    Export, share and cite



    Title :

    Changes in Monocyte Functions of Astronauts


    Contributors:
    Kaur, I. (author) / Simons, E. (author) / Castro, V. (author) / Ott, C. Mark (author) / Pierson, Duane L. (author)

    Publication date :

    2004-01-01


    Type of media :

    Miscellaneous


    Type of material :

    No indication


    Language :

    English




    Changes in Neutrophil Functions in Astronauts

    Kaur, Indreshpal / Simons, Elizabeth R. / Castro, Victoria et al. | NTRS | 2002


    Astronauts

    NTRS | 1988


    ANTIPODEAN ASTRONAUTS

    Burgess, Colin | Online Contents | 1998


    Commercial Astronauts

    Seedhouse, Erik | Springer Verlag | 2024


    NASA astronauts

    NTRS | 1966