Complex three-dimensional masses of normal human epithelial and mesenchymal small-intestine cells cocultured in process involving specially designed bioreactors. Useful as tissued models for studies of growth, regulatory, and differentiation processes in normal intestinal tissues; diseases of small intestine; and interactions between cells of small intestine and viruses causing disease both in small intestine and elsewhere in body. Process used to produce other tissue models, leading to advances in understanding of growth and differentiation in developing organisms, of renewal of tissue, and of treatment of myriad of clinical conditions. Prior articles describing design and use of rotating-wall culture vessels include "Growing And Assembling Cells Into Tissues" (MSC-21559), "High-Aspect-Ratio Rotating Cell-Culture Vessel" (MSC-21662), and "In Vitro, Matrix-Free Formation Of Solid Tumor Spheroids" (MSC-21843).
Three-Dimensional Coculture Of Human Small-Intestine Cells
NASA Tech Briefs ; 18 , 1
1994-01-01
Miscellaneous
No indication
English
Three-Dimensional Coculture of Human Small-Intestine Cells
Online Contents | 1994
Coculture Production of Butanol by Clostridium Bacteria
NTRS | 1985
|Blood and small intestine cell kinetics under radiation exposures: Mathematical modeling
Online Contents | 2009
|British Library Online Contents | 2014
Three-dimensional detonation cells
AIAA | 2002
|