Two different protein crystallizations, namely ,the free Fab fragment of the Je142 monoclonal antibody and the complex of Fab fragment/HPr with antigen, were performed aboard the Discovery Space Shuttle flights and the Mir space station, respectively. Medium sized crystals of the Je142 Fab fragment were obtained. The Je142 Fab fragment/Hpr complex produced two medium-sized crystals after two months aboard the Mir space station. Microgravity was found to eliminate the tendency of these crystals to form clusters.


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    Title :

    Protein crystallization aboard the Space Shuttle and the Mir space station



    Conference:

    AIAA, Aerospace Sciences Meeting and Exhibit ; 1993 ; Reno, NV, United States


    Publication date :

    1993-01-01


    Type of media :

    Conference paper


    Type of material :

    No indication


    Language :

    English





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