Morphological and enzymatic responses in fibers of different types were studied in rats after 14 days of spaceflight onboard Cosmos 2044 or hindlimb suspension. Fibers were classified as fast-twitch, slow-twitch, or both fast- and slow-twitch on the basis of the type of myosin heavy chains (MHC). Data obtained indicate that during the 14 days of spaceflight or suspension the protein profiles of 9-14 percents of the slow-twitch fibers reconfigured from typical slow-twitch toward fast switch fibers, while all fibers were dramatically losing total protein. These results were consistent with the data obtained from Cosmos 1887 and Skylab 3. It is suggested that effects of spaceflight on skeletal muscle can be attributed to a dramatic reduction in the level and/or pattern of loading.
Rat soleus muscle fiber responses to 14 days of spaceflight and hindlimb suspension
Journal of Applied Physiology, Supplement ; 73 , 2 Au
1992-08-01
Miscellaneous
No indication
English
Different responses in soleus muscle fibers of Wistar and Wistar Hannover rats to hindlimb unloading
British Library Conference Proceedings | 2005
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