The early cardiovascular adaptation to zero gravity, simulated by head-down tilt at 5 deg, was studied in a series of 10 normal young men. The validity of the model was confirmed by comparing the results with data from Apollo and Skylab flights. Tilt produced a significant central fluid shift with a transient increase in central venous pressure, later followed by an increase in left ventricular size without changes in cardiac output, arterial pressure, or contractile state. The hemodynamic changes were transient with a nearly complete return to the control state within 6 h. The adaptation included a diuresis and a decrease in blood volume, associated with ADH, renin, and aldosterone inhibition.


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    Title :

    Early cardiovascular adaptation to zero gravity simulated by head-down tilt


    Contributors:

    Conference:

    International Astronautical Federation, International Astronautical Congress


    Publication date :

    1979-09-01


    Type of media :

    Conference paper


    Type of material :

    No indication


    Language :

    English




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