The urinary excretion of conjugated and unconjugated 17-hydroxycorticosteroids (17-OHCS) was studied in 8 male students at 3 hour intervals during periods of 24 hours. Two 24 hour preflight periods revealed basic normal daily periodicity of 17-OHCS excretion. Effects of a 6 hour time shift were evaluated by determining the excretion rates after flight from Germany to the USA and vice versa on days 1, 3, 5, and 8 after arrival. A desynchronization with the local time was observed after flights in both directions, the diurnal 17-OHCS excretion patterns being more disturbed, however, after the West-East flight. The resynchronization time of maximum and mininum excretion was 3 to 5 days after the westward travel and 5 to 8 or more after traveling in the opposite direction. It is suggested that the unfavorable flight conditions of the West-East flight (night flight) mainly account for the more marked time shift effects observed after the eastward flight. (Author)
Effects of Time Shift on Diurnal Rhythms of 17-Hydroxy Corticosteroide Auswirkungen der Zeitverschiebung Auf die Tagesrhythmik der 17-Hydroxycorticosteroide
1973
68 pages
Report
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English