AbstractFour payload crewmembers were exposed to sustained linear acceleration in a centrifuge during the Neurolab (STS-90) flight. In contrast to previous studies, otolith–ocular reflexes were preserved during and after flight. This raised the possibility that artificial gravity may have acted as a countermeasure to the deconditioning of otolith–ocular reflexes. None of the astronauts who were centrifuged had orthostatic intolerance when tested with head-up passive tilt after flight. Thus, centrifugation may also have helped maintain post-flight hemodynamic responses to orthostasis by preserving the gain of the otolith–sympathetic reflex. A comparison with two fellow Neurolab orbiter crewmembers not exposed to artificial gravity provided some support for this hypothesis. One of the two had hemodynamic changes in response to post-flight tilt similar to orthostatically intolerant subjects from previous missions. More data is necessary to evaluate this hypothesis, but if it were proven correct, in-flight short-radius centrifugation may help counteract orthostatic intolerance after space flight.


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    Title :

    Artificial gravity: A possible countermeasure for post-flight orthostatic intolerance


    Contributors:

    Published in:

    Acta Astronautica ; 56 , 9-12 ; 867-876


    Publication date :

    2005-01-01


    Size :

    10 pages




    Type of media :

    Article (Journal)


    Type of material :

    Electronic Resource


    Language :

    English




    Artificial gravity: A possible countermeasure for post-flight orthostatic intolerance

    Moore, S. T. / Diedrich, A. / Biaggioni, I. et al. | British Library Conference Proceedings | 2005


    Artificial gravity: A possible countermeasure for post-flight orthostatic intolerance

    Moore, S. T. / Diedrich, A. / Biaggioni, I. et al. | British Library Conference Proceedings | 2005


    Post-Flight Orthostatic Intolerance

    Baisch, F. J. / Beck, L. E. J. | British Library Online Contents | 1997