Abstract We have been using the “premature chromosome condensation (PCC)” technique to investigate chromosomal breakage, rejoining and misrepair induced by accelerated heavy ions. With the presentation of new Fe experiments, we now review the available PCC data to summarize our current understanding of the action of high velocity charged particles on mammalian chromosomes. Implications for the survival RBE/LET relationship are also discussed.


    Access

    Check access

    Check availability in my library

    Order at Subito €


    Export, share and cite



    Title :

    Heavy ion-induced chromosomal damage and repair


    Contributors:

    Published in:

    Advances in Space Research ; 12 , 2-3 ; 81-89


    Publication date :

    1991-01-01


    Size :

    9 pages




    Type of media :

    Article (Journal)


    Type of material :

    Electronic Resource


    Language :

    English



    Repair and misrepair of heavy-ion-induced chromosomal damage

    Goodwin, E. / Blakely, E. / Ivery, G. et al. | Elsevier | 1989


    DNA Damage and Repair in Oncogenic Transformation by Heavy Ion Radiation

    Yang, T. C. / Mei, M. / George, K. A. et al. | British Library Conference Proceedings | 1995



    Repair of radiation-induced genetic damage under microgravity

    Pross, H. D. et al | British Library Online Contents | 1994