AbstractTo test the effectiveness of centrifuge-induced artificial gravity with ergometric exercise, 12 healthy young men ( 20.7 ± 1.9 yr ) were exposed to simulated microgravity for 14 days of - 6 head-down bedrest. Half the subjects were randomly selected and loaded 1.2G artificial gravity with 60W (four out of six subjects) or 40W (two out of six subjects) of ergometric workload on days 1 , 2 , 3 , 5 , 7 , 9 , 11 , 12 , 13 , 14 (CM group). The rest of the subjects served as the control. Anti-G score, defined as the G - load × running time to the endpoint, was significantly elongated by the load of the centrifuge-ergometer. Plasma volume loss was suppressed ( - 5.0 ± 2.4 vs. - 16.4 ± 1.9 % ), and fluid volume shift was prevented by the countermeasure load. Elevated heart rate and muscle sympathetic nerve activity after bedrest were counteracted, and exaggerated response to head-up tilt was also suppressed. Centrifuge-induced artificial gravity with exercise is effective in preventing cardiovascular deconditioning due to microgravity exposure, however, an effective and appropriate regimen (magnitude of G-load and exercise workload) should be determined in future studies.


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    Title :

    Effectiveness of centrifuge-induced artificial gravity with ergometric exercise as a countermeasure during simulated microgravity exposure in humans


    Contributors:

    Published in:

    Acta Astronautica ; 57 , 2-8 ; 75-80


    Publication date :

    2005-01-01


    Size :

    6 pages




    Type of media :

    Article (Journal)


    Type of material :

    Electronic Resource


    Language :

    English



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