Cardiovascular regulation is integral to life. Animal studies have identified both neural and endocrine pathways, by which the central nervous system adjusts cardiac output and peripheral vascular resistance to changing physiological demands. The outflow of these pathways is coordinated by various central nervous regions based on afferent information from baroreceptors, chemoreceptors, nociceptors, and circulating hormones, and is modulated by physiologic and behavioural state. In humans, however, knowledge on central cardiovascular regulation below the cortical level is scarce. Here, we show using functional MRI (fMRI) that at least three hypothalamic subsystems are involved in cardiovascular regulation in humans. The rhythmic behaviour of these systems corresponds to high and low frequency oscillations typically seen in blood pressure and heart rate variability.


    Access

    Download


    Export, share and cite



    Title :

    Deciphering the neural signature of human cardiovascular regulation


    Contributors:
    Manuel, J. (author) / Färber, N. (author) / Gerlach, D.A. (author) / Heusser, K. (author) / Jordan, J. (author) / Tank, J. (author) / Beissner, F. (author)

    Published in:

    eLife ; 9 ; e55316


    Publication date :

    2020-07-28



    Type of media :

    Article (Journal)


    Type of material :

    Electronic Resource


    Language :

    English




    Neural Approaches for Human Signature Verification

    Lee, L. L. | British Library Conference Proceedings | 1995


    Cardiovascular Regulation in Microgravity

    Blomqvist, G. A. / Lane, L. D. / Wright, S. J. et al. | British Library Online Contents | 1997


    SEOSAT/Ingenio Deciphering/Ciphering Units

    Alzu, I.H. / Palomo, A.G. / Caselles, J.F. et al. | British Library Conference Proceedings | 2013


    Deciphering Martian climatic history using returned samples

    Paige, D. A. / Krieger, D. B. / Brigham, C. A. | NTRS | 1988


    Identification of drone thermal signature by convolutional neural network

    Quan, Chong Yu / Edmond, Ong Le Wei / Srigrarom, Sutthiphong | IEEE | 2021