Health-related Quality of Life (HrQoL) is probably the most important outcome parameter for the evaluation and management of chronic diseases. As this parameter is subjective and prone to bias, there is an urgent need to identify objective surrogate markers. Gait velocity has been shown to be associated with HrQoL in numerous chronic diseases, such as Parkinson's disease (PD). With the development and wide availability of simple-to-use wearable sensors and sophisticated gait algorithms, kinematic gait parameters may soon be implemented in clinical routine management. However, the association of such kinematic gait parameters with HrQoL in PD has not been assessed to date.Kinematic gait parameters from a 20-meter walk from 43 PD patients were extracted using a validated wearable sensor system. They were compared with the Visual Analogue Scale of the Euro-Qol-5D (EQ-5D VAS) by performing a multiple regression analysis, with the International Classification of Functioning, Disability and Health (ICF) model as a framework.Use of assistive gait equipment, but no kinematic gait parameter, was significantly associated with HrQoL.The widely accepted concept of a positive association between gait velocity and HrQoL may, at least in PD, be driven by relatively independent parameters, such as assistive gait equipment.


    Access

    Download


    Export, share and cite



    Title :

    No relevant association of kinematic gait parameters with Health-related Quality of Life in Parkinson's disease.



    Publication date :

    2017-01-01


    Remarks:

    PLOS ONE 12(5), e0176816 (2017). doi:10.1371/journal.pone.0176816


    Type of media :

    Article (Journal)


    Type of material :

    Electronic Resource


    Language :

    English



    Classification :

    DDC:    629



    No relevant association of kinematic gait parameters with Health-related Quality of Life in Parkinson’s disease

    Bettecken, Kristina / Bernhard, Felix / Sartor, Jennifer et al. | BASE | 2017

    Free access

    A study on lower limb asymmetries in Parkinson’s Disease during gait assessed through kinematic-derived parameters

    Arippa, Federico / Leban, Bruno / Monticone, Marco et al. | BASE | 2022

    Free access

    Measuring gait quality in parkinson’s disease through real-time gait phase recognition

    Mileti, Ilaria / Germanotta, Marco / Di Sipio, Enrica et al. | BASE | 2018

    Free access


    Streaming Gait Assessment for Parkinson's Disease

    Flagg, Cristopher / Frieder, Ophir / MacAvaney, Sean et al. | TIBKAT | 2020