Alterations in cardiovascular regulation and function that occur during and after space flight have been reported. These alterations are manifested, for example, by reduced orthostatic tolerance upon reentry to the earth’s gravity from space. However, the precise physiologic mechanisms responsible for these alterations remain to be fully elucidated. Perhaps as a result, fully effective countermeasures have yet to be developed. The National Space Biomedical Research Institute Cardiovascular Alterations Team is currently conducting a head-down tilt bed rest study in Boston. These studies involve the application of two powerful new methodologies developed at the NASA Center for Quantitative Cardiovascular Physiology, Modeling and Data Analysis at the Massachusetts Institute of Technology—cardiovascular system identification and T Wave Alternans analysis—for the study of the effects of simulated microgravity on the cardiovascular system. This study is being used as a basis for developing effective countermeasures against microgravity induced orthostatic hypotension and ventricular arrhythmias.


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    Title :

    Non-invasive assessment of Alterations in Cardiovascular regulation and function and susceptibility to ventricular arrhythmias resulting from microgravity exposure



    Conference:

    SPACE TECHNOLOGY AND APPLICATIONS INTERNATIONAL FORUM - 2000 ; 2000 ; Albuquerque, New Mexico (USA)


    Published in:

    AIP Conference Proceedings ; 504 , 1 ; 281-294


    Publication date :

    2000-01-19


    Size :

    14 pages





    Type of media :

    Conference paper


    Type of material :

    Electronic Resource


    Language :

    English