Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2017. ; Cataloged from PDF version of thesis. ; Includes bibliographical references (pages 125-133). ; The generation of fast movements during sensorimotor control is fundamentally limited by the biophysics of neural activity and the physiological dynamics of the muscles involved. Yet, the limiting factors and the corresponding tradeoffs have not been rigorously quantified. We use feedback control principles to identify limitations in the ability of the sensorimotor control system to track intended fast periodic movements. We show that (i) a linear model for movement generation fails to predict known undesirable phenomena encountered in the regime of fast movements, and (ii) the theory of pulsatile control of movement generation allows us to correctly characterize fundamental limitations in this regime. This thesis identifies the fastest periodic movement possible for given musculoskeletal and neuronal dynamics, which has far-reaching implications in sensorimotor control. The use of neuronal decoders in the Brain Machine Interface setting is discussed; we introduce a real-time decoder of neuronal activity, and derive conditions for its stability in the presence of feedback. The framework developed in this thesis allows us to characterize the effect of compromised neural and physiological activity on movement, and guide the design of corresponding therapeutic measures. ; by Shreya Saxena. ; Ph. D.


    Zugriff

    Download


    Exportieren, teilen und zitieren



    Titel :

    Moving fast : neural constraints in closed loop ; Neural constraints in closed loop



    Erscheinungsdatum :

    2017-01-01


    Anmerkungen:

    1023862488


    Medientyp :

    Hochschulschrift


    Format :

    Elektronische Ressource


    Sprache :

    Englisch



    Klassifikation :

    DDC:    629





    Multifunctional Neural Interfaces for Closed-Loop Control of Neural Activity

    Chapman, CAR / Goshi, N / Seker, E | BASE | 2018

    Freier Zugriff

    Transmission method of closed-loop elevator and closed-loop elevator

    PENG ZHONGLIANG / ZHAO ANLI / ZHOU JIAN | Europäisches Patentamt | 2021

    Freier Zugriff

    A New Neuro-Based Solution for Closed-Loop Optimal Guidance with Terminal Constraints

    Rahbar, N. / Bahrami, M. / Menhaj, M. et al. | British Library Conference Proceedings | 1999