Starting from a mathematical model which describes the dynamics of Chronic Myelogenous Leukemia (CML) when the action of different cell lines of the immune system is considered, the aim of the paper is to analyze the parameters influence in CML evolution. The model consists of seven delay differential equations with seven delays. The physiological processes are modeled using feedback functions so the variation of their coefficients changes the disease's evolution. Numerical simulations will be used to observe the evolution of the disease and to determine the possible treatment options.


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    Titel :

    Parameter analysis for a mathematical model of the immune system in leukemia


    Beteiligte:
    Safta, Carmen Anca (Autor:in) / Balea, Silvia (Autor:in) / Halanay, Andrei (Autor:in) / Neamtu, Mihaela (Autor:in) / Sivasundaram, Seenith (Herausgeber:in)

    Kongress:

    10TH INTERNATIONAL CONFERENCE ON MATHEMATICAL PROBLEMS IN ENGINEERING, AEROSPACE AND SCIENCES: ICNPAA 2014 ; 2014 ; Narvik, Norway


    Erschienen in:

    AIP Conference Proceedings ; 1637 , 1 ; 1307-1315


    Erscheinungsdatum :

    10.12.2014


    Format / Umfang :

    9 pages





    Medientyp :

    Aufsatz (Konferenz)


    Format :

    Elektronische Ressource


    Sprache :

    Englisch



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