Parameters of bone formation and resorption were measured in rats orbited for 19.5 days aboard the Soviet Cosmos 782 biological satellite. The most striking effects were on bone formation. During flight, rats formed significantly less periosteal bone than did control rats on the ground. An arrest line at both the periosteum and the endosteum of flight animals suggests that a complete cecessation of bone growth occurred. During a 26-day postflight period, the defect in bone formation was corrected. No significant changes in bone resorption were observed.


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    Title :

    Inhibition of bone formation during space flight


    Contributors:

    Published in:

    Science ; 201


    Publication date :

    1978-09-22


    Type of media :

    Miscellaneous


    Type of material :

    No indication


    Language :

    English




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