The results of a series of antimotion sickness drug evaluations indicates that drugs with central anticholinergic actions and drugs that increase central sympathetic activity are effective against motion sickness. The combination of these actions produces a synergistic effect against motion sickness. The effect of these medications on central acetylcholine or on norepinephrine could alter a balance between the neurons in the vestibular and reticular areas which influence motion sickness and also sympathetic and parasympathetic reactions. It is suggested that this could be their mechanism of action in preventing motion sickness.


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    Title :

    Theory of antimotion sickness drug mechanisms.


    Contributors:
    Wood, D. C. (author) / Graybiel, A. (author)

    Published in:

    Publication date :

    1972-03-01


    Type of media :

    Miscellaneous


    Type of material :

    No indication


    Language :

    English


    Keywords :






    MARINE ANTIMOTION DEVICE

    SUGINAMI YASUYUKI | European Patent Office | 2022

    Free access