Third degree frostbite was produced in five Hanford Miniature Swine exposed to chilled air. Biopsies were taken. The 200 slides were evaluated microscopically: epithelial necrosis and regeneration were recorded as absent or present. Vascular degeneration, thrombosis, sweat gland injury, and subcutis injury were ranked. Epithelial necrosis and/or regeneration were seen consistently, but not until 1-2 weeks after injury. Vascular injury was absent for the 1 minute freeze, but was seen by 48 hours for the 5, 10, and 20 minute freezes. Sweat gland injury was seen by 12 hours for all freezes except the 1 minute freeze. Subcutis changes were seen 1-2 weeks after injury.
Experimental Third Degree Frostbite in Hanford Miniature Swine
1987
23 pages
Report
No indication
English
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