The present invention relates to Tetracyclic Heterocycle Compounds of Formulaand pharmaceutically acceptable salts or prodrug thereof, wherein A, X, R1, R2, R3 and Ware as defined herein. The present invention also relates to compositions comprising at least one Tetracyclic Heterocycle Compound, and methods of using the Tetracyclic Heterocycle Compounds for treating or preventing HIV infection in a subject.


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    Title :

    Tetracyclic heterocycle compounds useful as HIV integrase inhibitors


    Contributors:
    GRAHAM THOMAS H (author) / YU TAO (author) / ZHANG YONGLIAN (author) / MCCAULEY JOHN A (author)

    Publication date :

    2022-06-14


    Type of media :

    Patent


    Type of material :

    Electronic Resource


    Language :

    English


    Classification :

    IPC:    A61K Zubereitungen für medizinische, zahnärztliche oder kosmetische Zwecke , PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES / A61P SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS , Spezifische therapeutische Aktivität von chemischen Verbindungen oder medizinischen Zubereitungen / B64C AEROPLANES , Flugzeuge / C07D HETEROCYCLIC COMPOUNDS , Heterocyclische Verbindungen / C12N Mikroorganismen oder Enzyme , MICROORGANISMS OR ENZYMES



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    GRAHAM THOMAS H / YU TAO / ZHANG YONGLIAN et al. | European Patent Office | 2021

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