Background/Aim. Prostate delineation, pre-planning and catheter implantation procedures, in high-dose rate brachy-therapy (HDR-BT), are commonly based on the prostate manually segmented transrectal ultrasound (TRUS) images. The aim of this study was to quantitatively analyze the consis-tency of prostate capsule delineation, done by a single thera-pist, prior to each HDR-BT fraction and the changes in the shape of the prostate capsule during HDR-BT, using two di-mensional (2D) TRUS axial image. Methods. A group of 16 patients were treated at the Medical System Belgrade Brachy-therapy Department with definitive HDR-BT. The total ap-plied median dose of 52 Gy was divided into four individual fractions, each fraction being delivered 2–3 weeks apart. Real time prostate axial visualization and the manual segmentation prior to each fraction were performed using B-K Medical ul-trasound. Quantitative analyses, analysis of an area and shape were applied on 2D-TRUS axial images of the prostate. Area analyses were used to calculate the average value of the cross-sectional area of the prostate image. The parameters of the prostate shape, the fractal dimension and the circularity ratio of the prostate capsule contour were estimated at the maximum axial cross section of the prostate image. Results.The sample group consisted of four phases, each phase being performed prior to the first, second, third and fourth HDR-BT fraction, respectively. Statistical analysis showed that dur-ing HDR-BT fractions there were no significant differences in the average value of area, as well as in the maximum shape of prostate capsule. Conclusions. Quantitative analysis of TRUS axial prostate segmented images shows a successful capsule delineation in the series of manually segmented TRUS images, and the prostate maximum shape remaining unchanged during HDR-BT fractions.


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    Title :

    A quantitative analysis of two-dimensional manually segmented transrectal ultrasound axial images in planning high dose rate brachytherapy for prostate cancer



    Publication date :

    2017-01-18


    Remarks:

    oai:zenodo.org:3713190
    Vojnosanitetski pregled 74(5) 420-427



    Type of media :

    Article (Journal)


    Type of material :

    Electronic Resource


    Language :

    English



    Classification :

    DDC:    629







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