Background Chronic Fatigue Syndrome sCFS) is characterised by persistent fatigue, disability and a range of other symptoms. The PACE trial was randomised to compare four non-pharmacological treatments for patients with CFS in secondary care clinics. The aims of this sub study were to describe the use of complementary and alternative medicine (CAM) in the trial sample and to test whether CAM use correlated with an improved outcome. Method CAM use was recorded at baseline and 52 weeks. Logistic and multiple regression models explored relationships between CAM use and both patient characteristics and trial outcomes. Results At baseline, 450/640 (70%) of participants used any sort of CAM; 199/640 (31%) participants were seeing a CAM practitioner and 410/640 (64%) were taking a CAM medication. At 52 weeks, those using any CAM fell to 379/589 (64%). Independent predictors of CAM use at baseline were female gender, local ME group membership, prior duration of CFS and treatment preference. At 52 weeks, the associated variables were being female, local ME group membership, and not being randomised to the preferred trial arm. There were no significant associations between any CAM use and fatigue at either baseline or 52 weeks. CAM use at baseline was associated with a mean (CI) difference of 4.10 (1.28, 6.91; p = 0.024) increased SF36 physical function score at 52 weeks, which did not reach the threshold for a clinically important difference. Conclusion CAM use is common in patients with CFS. It was not associated with any clinically important trial outcomes.


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    Title :

    Complementary and alternative healthcare use by participants in the PACE trial of treatments for chronic fatigue syndrome


    Contributors:
    Lewith, G. (author) / Stuart, B. (author) / Chalder, T. (author) / McDermott, C. (author) / White, P.D. (author)

    Publication date :

    2016-06-10


    Remarks:

    Lewith , G , Stuart , B , Chalder , T , McDermott , C & White , P D 2016 , ' Complementary and alternative healthcare use by participants in the PACE trial of treatments for chronic fatigue syndrome ' , Journal of Psychosomatic Research . https://doi.org/10.1016/j.jpsychores.2016.06.005



    Type of media :

    Article (Journal)


    Type of material :

    Electronic Resource


    Language :

    English



    Classification :

    DDC:    629



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