Biodegradable stent prototypes were produced from poly L-lactic acid polytners with different molecular weights. The effects of molecular weight, drug incorporation and stent design on the collapse pressure of the stents were evaluated. While molecular weights did not show a significant effect on the collapse pressure of the stents, drug incorporation at high percentage decreased the collapse pressure of the stents substantially. Cryogenic fracture surfaces showed significant drug agglomeration as the concentration increased. The design of the stent was also found to a have significant effect on the collapse pressure. The stent produced from the same material has a higher collapse pressure when the load hearing surface area is increased.


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    Titel :

    Collapse pressures of biodegradable stents


    Beteiligte:
    Venkatraman, S. (Autor:in) / Poh, T.L. (Autor:in) / Vinalia, T. (Autor:in) / Mak, K.H. (Autor:in) / Boey, F. (Autor:in)

    Erschienen in:

    Biomaterials ; 24 , 12 ; 2105-2112


    Erscheinungsdatum :

    2003


    Format / Umfang :

    8 Seiten, 9 Bilder, 2 Tabellen, 20 Quellen




    Medientyp :

    Aufsatz (Zeitschrift)


    Format :

    Print


    Sprache :

    Englisch





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