We report a chemical sensing technology composed of engineered bioluminescent bacteria placed on an integrated microluminometer. The bacteria have been engineered to luminesce when the targeted compound is metabolized, while the microluminometer detects, processes, and then reports the magnitude of this optical signal. In this work we report our progress in the development of these biosensors and present data from our prototypes.


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    Titel :

    Bioluminescent Bioreporter Integrated Circuits (BBICs): Whole-Cell Environmental Monitoring Devices


    Weitere Titelangaben:

    Sae Technical Papers


    Beteiligte:
    Applegate, Bruce M. (Autor:in) / Arnott, Chris (Autor:in) / Nivens, David E. (Autor:in) / Bolton, Eric (Autor:in) / Sayler, Gary S. (Autor:in) / Jellison, Gerald E. (Autor:in) / Patterson, Greg (Autor:in) / Dionisi, Hebe M. (Autor:in) / Rochelle, James (Autor:in) / Paulus, Michael J. (Autor:in)

    Kongress:

    International Conference On Environmental Systems ; 2000



    Erscheinungsdatum :

    2000-07-10




    Medientyp :

    Aufsatz (Konferenz)


    Format :

    Print


    Sprache :

    Englisch




    Bioluminescent Bioreporter Integrated Circuits (BBICs): Whole-Cell Environmental Monitoring Devices1

    Applegate, Bruce M. / Nivens, David E. / Sayler, Gary S. et al. | SAE Technical Papers | 1999



    Quantitative bioluminescent detection of bacteria

    Chappelle, E. W. / Picciolo, G. L. | NTRS | 1976


    Bioluminescent Assays for High-Throughput Screening

    Fan, F. / Wood, K. V. | British Library Online Contents | 2007


    Germanium devices for integrated photonic circuits

    Hopkins, F. K. / Benken, Alexander / Walsh, Kevin M. et al. | SPIE | 2014