Abstract The mechanism of the condensation of dilute aqueous solutions of HCN and the products formed by these reactions have been investigated. The initial HCN condensation reactions yield3, a compound which is readily oxidized to4. A similar oxidation of5 to6 was also observed. Urea is formed on hydrolysis of4. The oxidation-reduction products formed from HCN may be in part a consequence of the oxidation of3. It has been established by combination GC/MS that the amino acids glycine, diaminosuccinic acid, α-amino-isobutyric acid, aspartic acid, alanine and isoleucine are released on acid hydrolysis of the ‘HCN polymer’. Hydantoin (7), 5,5-dimethylhydantoin (8) and 5-carboxymethyldenehydantoin (10) are also released on acid hydrolysis of the HCN condensation products. The direct conversion of the dicarbonyl derivative, of diaminosuccinic acid to orotic acid via10 at pH 8 has been observed. This conversion suggests a direct route to pyrimidines from HCN.


    Zugriff

    Zugriff über TIB

    Verfügbarkeit in meiner Bibliothek prüfen

    Bestellung bei Subito €


    Exportieren, teilen und zitieren



    Titel :

    Biomolecules from HCN


    Beteiligte:
    Ferris, J. P. (Autor:in) / Wos, J. D. (Autor:in) / Ryan, T. J. (Autor:in) / Lobo, A. P. (Autor:in) / Donner, D. B. (Autor:in)

    Erschienen in:

    Erscheinungsdatum :

    1974




    Medientyp :

    Aufsatz (Zeitschrift)


    Format :

    Print


    Sprache :

    Englisch



    Klassifikation :

    Lokalklassifikation TIB:    535/3908/4290
    BKL:    44.71 Verkehrsmedizin



    Microscopy for Recognition of Individual Biomolecules

    Schmidt, T. / Hinterdorfer, P. / Schindler, H. | British Library Online Contents | 1997


    Photochemical synthesis of biomolecules under anoxic conditions

    Folsome, Clair / Brittain, Andrew / Zelko, Michael | Online Contents | 1983


    Observation of THz region vibrational spectra in biomolecules

    Ishikawa, Y. / Minamide, H. / Ikari, T. et al. | IEEE | 2003


    Biomolecules in the Interstellar Medium and in Comets

    Charnley, S. B. / Rodgers, S. D. / Kuan, Y.-J. et al. | British Library Conference Proceedings | 2002


    Observation of THz region vibrational spectra in biomolecules

    Ishikawa, Y. / Minamide, H. / Ikari, T. et al. | British Library Conference Proceedings | 2003