Susceptibility of healthy astronauts to orthostatic hypotension and presyncope is exacerbated upon return from spaceflight. Hypo-volemia is suspected to play an important role in cardiovascular deconditioning following exposure to spaceflight, which may lead to increased peripheral resistance, attenuated arterial baroreflex, and changes in cardiac function. The effect of altered gravity during space flight and planetary transition on human cardiovascular function is of critical importance to maintenance of astronaut health and safety. A promising countermeasure for post-flight orthostatic intolerance is fluid loading used to restore loss fluid volume by giving crew salt tablets and water prior to re-entry. Eight men and eight women will be tested during two, 6-hour exposures to 6o HDT: 1) fluid loading, 2) no fluid loading. Before and immediately after each HDT, subjects will perform a stand test to assess their orthostatic tolerance. Physiological measures (e.g., ECG, blood pressure, peripheral blood volume) will be continuously monitored while echocardiography measures are recorded at 30-minute intervals during HDT and stand tests. Preliminary results (N=4) clearly show individual differences in responses to this countermeasure and the time course of physiological changes induced by HDT.


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    Titel :

    Individual Differences in the Temporal Profile of Cardiovascular Responses to Head Down Tilt and Orthostatic Stress with and Without Fluid Loading


    Beteiligte:

    Kongress:

    NASA Human Research Program Investigators Workshop ; 2013 ; Galveston, TX, United States


    Erscheinungsdatum :

    12.02.2013


    Medientyp :

    Sonstige


    Format :

    Keine Angabe


    Sprache :

    Englisch


    Schlagwörter :




    Individual differences of cerebrovascular responses to gravitational stress - prediction of orthostatic intolerance

    Ueno, T. / Yoshimoto, S. / Mayanagi, Y. et al. | British Library Conference Proceedings | 1994



    PHYSIOLOGICAL MONITORING OF FLUID SHIFTS DURING ORTHOSTATIC TILT

    Strangmann, G.E. / Marshall-Goebel, K. / Moestl, Stefan et al. | Deutsches Zentrum für Luft- und Raumfahrt (DLR) | 2020

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