The influence of a 13.8-day spaceflight and about 8.5-11 h of recovery at 1 g on fibro blastlike osteoblast precursor cells was assessed in the periodontal ligament of rat maxillary first molars. Preosteoblasts (C + D cells), less differentiated progenitor cells (A + A prime cells), and nonosteogenic fibroblastlike cells (B cells) were identified by nuclear volume analysis. No differences were observed among flight, synchronous vivarium, and basal control groups in the A + A prime or C + D cell compartments. Compared with previous spaceflight experiments, the present data are consistent with a postflight response to replinish preosteoblasts and restore periodontal ligament osteogenic potential. These data emphasize the need to unequivocally determine the flight effect by killing the animals in-flight and further assess the postflight recovery phenomenon.


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    Titel :

    Preosteoblast production in Cosmos 2044 rats - Short-term recovery of osteogenic potential


    Beteiligte:


    Erscheinungsdatum :

    01.08.1992



    Medientyp :

    Sonstige


    Format :

    Keine Angabe


    Sprache :

    Englisch




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