To test the possibility that spaceflight has a deleterious effect on bone mechanical properties, femur breaking strength by torsional loading in rats that had been flown for 19 days aboard Cosmos 936 was determined. The results showed that femurs from flight rats were less stiff than the flight controls, and failed under torsion at a lower torque and energy of absorption. The defect was corrected following space flight and could be prevented during space flight by centrifuging the rats at 1 x g. Altered bone geometry due to inhibition of bone formation at the periosteal surface provides the most likely explanation for the decrease in bone strength during spaceflight.


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    Titel :

    Effect of space flight on bone strength


    Beteiligte:
    Spengler, D. M. (Autor:in) / Morey, E. R. (Autor:in) / Carter, D. R. (Autor:in) / Turner, R. T. (Autor:in) / Baylink, D. J. (Autor:in)

    Erschienen in:

    Erscheinungsdatum :

    01.01.1982


    Medientyp :

    Sonstige


    Format :

    Keine Angabe


    Sprache :

    Englisch






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    Doty, S.B. | Tema Archiv | 2004


    Inhibition of bone formation during space flight

    Morey, E. R. / Baylink, D. J. | NTRS | 1978


    Countermeasures against space flight related bone loss

    Leblanc, Adrian / Schneider, Victor | NTRS | 1992