The urinary excretion of unconjugated 17-hydroxycorticosteroids (17-OHCS) was studied in 8 male students in 3-hour intervals during periods of 24 hours. Two 24-hour preflight periods revealed the basic normal daily periodicity of 17-OHCS excretion. Effects of a 6-hour time shift were evaluated by determining the excretion rates after flights from Cologne/Germany to Chicago/U.S.A. and vice versa on day 1, 3, 5, and 8 after arrival. A desynchronization with the new local time was observed after flights in both directions, the diurnal 17-OHCS excretion patterns being more disturbed, however, after the West-East flight. The resynchronization time of maximum and minimum excretion was about 5-8 days after the westward travel and more than 8 days after traveling in the opposite direction. It is suggested that an unfavorable flight schedule, which at present is practiced by most airlines for flights going from the U.S.A. to Europe, mainly accounts for the more marked time shift effects observed after the eastward flight. (Author)


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    Titel :

    Effects of Transmeridian Flights on the Diurnal Excretion Pattern of 17-Hydroxycorticosteroids


    Beteiligte:
    H. M. Wegmann (Autor:in) / H. Bruner (Autor:in) / D. Jovy (Autor:in) / K. E. Klein (Autor:in) / J. P. Marbarger (Autor:in)

    Erscheinungsdatum :

    1970


    Format / Umfang :

    4 pages


    Medientyp :

    Report


    Format :

    Keine Angabe


    Sprache :

    Englisch