Astronauts experience psychological and physical stresses that may result in re-activation of latent viruses during spaceflight, potentially increasing the risk of disease among crew members. The shedding of Epstein-Barr virus (EBV) in the saliva of astronauts will increase during spaceflight. A total of 534 saliva specimens were collected from 11 EBV-seropositive astronauts before, during, and after four space shuttle missions. The presence of EBV DNA in saliva, assessed by polymerase chain reaction (PCR), was used to determine shedding patterns before, during, and after spaceflight. EBV DNA was detected more frequently before flight than during (p less than 0.001) or after (p less than 0.01) flight. No significant difference between the in-flight and postflight periods was detected in the frequency of occurrence of EBV DNA. The increased frequency of shedding of EBV before flight suggests that stress levels may be greater before launch than during or after spaceflight.


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    Titel :

    Incidence of Epstein-Barr Virus in Astronaut Saliva During Spaceflight


    Beteiligte:
    D. A. Payne (Autor:in) / S. K. Mehta (Autor:in) / S. K. Tyring (Autor:in) / R. P. Stowe (Autor:in) / D. L. Pierson (Autor:in)

    Erscheinungsdatum :

    1998


    Format / Umfang :

    14 pages


    Medientyp :

    Report


    Format :

    Keine Angabe


    Sprache :

    Englisch




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    Increased EBV Shedding in Astronaut Saliva During Spaceflight

    Pierson, D. L. / Stowe, R. P. / Phillips, T. et al. | NTRS | 2003


    Government Astronaut Participation In Suborbital Spaceflight

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    Lytic Replication of Epstein-Barr Virus During Space Flight

    Stowe, R. P. / Pierson, D. L. / Barrett, A. D. T. | NTRS | 1999


    Government Astronaut Participation In Suborbital Spaceflight

    B. T. Hill / E. Blome / R. W. Seibold | NTIS | 2021