We present BARD (biological arc diagrams), a visualization tool for biological sequence analysis. The development of BARD began with the application of Wattenberg's arc diagrams (Wattenberg, 2002) to results from sequence analysis programs, such as BLAST (Atschul et al., 1990). In this paper, we extend the initial arc diagram concept in two ways: 1) by separating the visualization method from the underlying matching algorithm and 2) by expanding the types of matches to include inexact matches, complemented palindrome matches, and inter-sequence matches. BARD renders each type of match distinctly, resulting in a powerful tool to quickly understand sequence similarities and differences. We illustrate the power of BARD by applying the technique to a comparative sequence analysis of the human pathogenic fungi Cryptococcus neoformans.
BARD: a visualization tool for biological sequence analysis
01.01.2003
367515 byte
Aufsatz (Konferenz)
Elektronische Ressource
Englisch
BARD: A visualization Tool for Biological Sequence Analysis
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