The present disclosure relates to the use of diaryl macrocycles in conjunction with MAPK/ERK kinase-1 and 2 (MEK1 and MEK2; the present invention relates to methods and compositions for the treatment of cancer using combinations of inhibitors of MAP2K1 and MAP2K2, such as trametinib.
本公开涉及用二芳基巨环与MAPK/ERK激酶‑1和‑2(MEK1和MEK2;MAP2K1和MAP2K2)的抑制剂,如曲美替尼的组合来治疗癌症的方法和组合物。
Combination therapy involving diaryl macrocyclic compounds
涉及二芳基巨环化合物的组合疗法
2022-08-05
Patent
Elektronische Ressource
Chinesisch
IPC: | B60H ARRANGEMENTS OR ADAPTATIONS OF HEATING, COOLING, VENTILATING, OR OTHER AIR-TREATING DEVICES SPECIALLY FOR PASSENGER OR GOODS SPACES OF VEHICLES , Anordnung oder Einbau der Heizung, Kühlung, Lüftung oder anderer Luftbehandlungsvorrichtungen für die Fahrzeugräume für Reisende oder Fracht / F24F Klimatisierung , AIR-CONDITIONING / F25B Kältemaschinen, Kälteanlagen oder Kälteverfahren , REFRIGERATION MACHINES, PLANTS, OR SYSTEMS |
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