AbstractVarious mutagenic effects by heavy ions were studied in bacteria, irradiated at accelerators in Dubna, Prague, Berkeley or Darmstadt. Endpoints investigated are histidine reversion (B. subtilis, S. typhimurium), azide resistance (B. subtilis), mutation in the lactose operon (E. coli), SOS chromotest (E. coli) and λ-prophage induction (E. coli). It was found that the cross sections of the different endpoints show a similar dependence on energy. For light ions (Z ≤ 4) the cross section decreases with increasing energy. For ions of Z = 10, it is nearly independent of energy. For heavier ions (Z ≥ 26) it increases with energy up to a maximum or saturation. The increment becomes steeper with increasing Z. This dependence on energy suggests a “mutagenic belt” inside the track that is restricted to an area where the density of departed energy is low enough not to kill the cell, but high enough to induce mutations.
Mutagenic effects of heavy ions in bacteria
Advances in Space Research ; 14 , 10 ; 315-329
1994-01-01
15 pages
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
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