Abstract V79 Chinese hamster cells were exposed to heavy ions (O to U) and assayed for mutants at the HGPRT-locus by incubation in selective medium containing 6-thioguanine. The LET ranged from 300 to 18000 keV/μm. Mutants could be recovered from all particle radiation but the effectivity per deposited energy decreased with atomic numbers greater than 8. The results are discussed with regard to fundamental processes of cell reactions to very heavy ions and with respect to possible implications for hazard estimations.
Mutation induction in mammalian cells by very heavy ions
Advances in Space Research ; 12 , 2-3 ; 111-118
01.01.1991
8 pages
Aufsatz (Zeitschrift)
Elektronische Ressource
Englisch
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