Abstract Gravity has been a pervasive influence on all living systems and there is convincing evidence to suggest that it alters fertilization and embryogenesis in several developmental systems. Notwithstanding the global importance of gravity on development, it has only been recently possible to begin to design experiments which might directly investigate the specific effects of this vector. The goal of this research program is to explore and understand the effects of gravity on fertilization and early development using sea urchins as a model system. Sea urchin development has several advantages for this project including the feasibility of maintaining and manipulating these cells during spaceflight, the high percentage of normal fertilization and early development, and the abundant knowledge about molecular, biochemical, and cellular events during embryogenesis which permits detailed insights into the mechanism by which gravity might interfere with development. Furthermore, skeletal calcium is deposited into the embryonic spicules within a day of fertilization permitting studies of the effects of gravity on bone calcium deposition.


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    Titel :

    Microgravity effects on sea urchin fertilization and development


    Beteiligte:
    Steffen, S. (Autor:in) / Fiser, R. (Autor:in) / Simerly, C. (Autor:in) / Schatten, H. (Autor:in) / Schatten, G. (Autor:in)

    Erschienen in:

    Advances in Space Research ; 12 , 1 ; 167-173


    Erscheinungsdatum :

    1991-01-01


    Format / Umfang :

    7 pages




    Medientyp :

    Aufsatz (Zeitschrift)


    Format :

    Elektronische Ressource


    Sprache :

    Englisch



    Microgravity effects of sea urchin fertilization and development

    Steffen, S. / Simerly, C. / Schatten, H. et al. | NTRS | 1992


    Sea urchin eggs under microgravity conditions

    Marthy, H.-J. | British Library Online Contents | 1997


    In vivo fertilization and development in microgravity using pleurodele (“Zeus” project)

    Grinfeld, S. / Dournon, C. / Houillon, C. et al. | Elsevier | 1994


    Fertilization of sea urchin eggs in space and subsequent development under normal conditions

    Marthy, Hans-Jürg / Schatt, Philippe / Santella, Luigia | Elsevier | 1994


    In Vivo Fertilization and Development in Microgravity Using Pleurodele ("Zeus" Project)

    Grinfeld, S. / Dournon, C. / Houillon, C. et al. | British Library Conference Proceedings | 1994