A key approach for designing bioinspired machines is to transfer concepts from nature to man-made structures by integrating biomolecules into artificial mechanical systems. This strategy allows the conversion of molecular information into macroscopic action. Here, we describe the design and dynamic behaviour of hybrid bioelectrochemical swimmers that move spontaneously at the air–water interface. Their motion is governed by the diastereomeric interactions between immobilized enantiopure oligo- mers and the enantiomers of a chiral probe molecule present in solution. These dynamic bipolar systems are able to convert chiral information present at the molecular level into enantiospecific macroscopic trajectories. Depending on the enantiomer in solution, the swimmers will move clockwise or anticlockwise.; the concept can also be used for the direct visualization of the degree of enantiomeric excess by analysing the curvature of the trajectories. Deciphering in such a straightforward way the enantiomeric ratio could be useful for biomedical applications, for the read-out of food quality or as a more general analogue of polarimetric measurements.


    Zugriff

    Download


    Exportieren, teilen und zitieren



    Titel :

    Direct dynamic read-out of molecular chirality with autonomous enzyme-driven swimmers


    Beteiligte:
    S. Arnaboldi (Autor:in) / G. Salinas (Autor:in) / A. Karajić (Autor:in) / P. Garrigue (Autor:in) / T. Benincori (Autor:in) / G. Bonetti (Autor:in) / R. Cirilli (Autor:in) / S. Bichon (Autor:in) / S. Gounel (Autor:in) / N. Mano (Autor:in)

    Erscheinungsdatum :

    01.12.2021



    Medientyp :

    Aufsatz (Zeitschrift)


    Format :

    Elektronische Ressource


    Sprache :

    Englisch



    Klassifikation :

    DDC:    629



    SAFETY SYSTEM FOR SWIMMERS INCLUDING VISUALLY IMPAIRED AND ELDERLY SWIMMERS

    FISHER AMIT | Europäisches Patentamt | 2025

    Freier Zugriff

    Breathing aid for swimmers

    WEIGNER MATHIAS | Europäisches Patentamt | 2016

    Freier Zugriff

    SWIM - Sensing With Independent Micro-swimmers

    Hao, Zhijian / Kim, Jea Du / Tosi, Phillipe et al. | NTRS | 2021


    SWIM - Sensing With Independent Micro-Swimmers

    Smith, Miles / Jae-Lee, Hyeong / Howell, Samuel et al. | NTRS | 2021