Abstract The γ-irradiation of malic acid in aqueous solutions was studied under initially oxygenated and oxygen-free conditions in an attempt to determine the possible interconversion of malic acid into other carboxylic acids, specifically those associated with Krebs cycle. The effect of dose on product formation of the system was investigated. Gas-liquid chromatography combined with mass spectrometry was used as the principal means of identification of the non-volatile products. Thin layer chromotography and direct probe mass spectroscopy were also employed. The findings show that a variety of carboxylic acids are formed, with malonic and succinic acids in greatest abundance. These products have all been identified as being formed in the γ-irradiation of acetic acid, suggesting a common intermediary. Since these molecules fit into a metabolic cycle, it is strongly suggestive that prebiotic pathways provided the basis for biological systems.


    Zugriff

    Zugriff über TIB

    Verfügbarkeit in meiner Bibliothek prüfen

    Bestellung bei Subito €


    Exportieren, teilen und zitieren



    Titel :

    γ-Irradiation of malic acid in aqueous solutions


    Beteiligte:

    Erschienen in:

    Erscheinungsdatum :

    1980




    Medientyp :

    Aufsatz (Zeitschrift)


    Format :

    Print


    Sprache :

    Englisch



    Klassifikation :

    Lokalklassifikation TIB:    535/3908/4290
    BKL:    44.71 Verkehrsmedizin



    Ionic Complexes of Biosynthetic Poly(malic acid) and Poly(glutamic acid) as Prospective Drug-Delivery Systems

    Portilla-Arias, J. A. / Garcia-Alvarez, M. / de Ilarduya, A. M. et al. | British Library Online Contents | 2007


    Glovebox Experiments with Malic Enzyme on USML-1

    Einspahr, H. M. / Clancy, L. L. / Finzel, B. C. et al. | British Library Conference Proceedings | 1995


    Synthesis, Degradability, and Drug Releasing Properties of Methyl Esters of Fungal Poly( beta ,L-malic acid)

    Portilla-Arias, J.A. / Garcia-Alvarez, M. / de Ilarduya, A.M. et al. | British Library Online Contents | 2008


    Biodegradable Nanoparticles of Partially Methylated Fungal Poly( beta -L-malic acid) as a Novel Protein Delivery Carrier

    Portilla-Arias, J.A. / Garcia-Alvarez, M. / Galbis, J.A. et al. | British Library Online Contents | 2008


    Solubility of boric acid in aqueous solutions of chloride salts

    Di Giacomo, G. / Brandani, P. / Brandani, V. et al. | Tema Archiv | 1993