Spacelab Life Sciences-3 (SLS-3) was scheduled to be the first United States man-tended microgravity flight containing Rhesus monkeys. The goal of this flight as in the five untended Russian COSMOS Bion flights and an earlier American Biosatellite flight, was to understand the biomedical and biological effects of a microgravity environment using the non-human primate as human surrogate. The SLS-3/Rhesus Project and COSMOS Primate-BIOS flights all utilized the rhesus monkey, Macaca mulatta. The ultimate objective of all flights with an animal surrogate has been to evaluate and understand biological mechanisms at both the system and cellular level, thus enabling rational effective countermeasures for future long duration human activity under microgravity conditions and enabling technical application to correction of common human physiological problems within earth's gravity, e.g., muscle strength and reloading, osteoporosis, immune deficiency diseases. Hardware developed for the SLS-3/Rhesus Project was the result of a joint effort with the French Centre National d'Etudes Spatiales (CNES) and the United States National Aeronautics and Space Administration (NASA) extending over the last decade. The flight hardware design and development required implementation of sufficient automation to insure flight crew and animal bio-isolation and maintenance with minimal impact to crew activities. A variety of hardware of varying functional capabilities was developed to support the scientific objectives of the original 22 combined French and American experiments, along with 5 Russian co-investigations, including musculoskeletal, metabolic, and behavioral studies. Unique elements of the Rhesus Research Facility (RRF) included separation of waste for daily delivery of urine and fecal samples for metabolic studies and a psychomotor test system for behavioral studies along with monitored food measurement. As in untended flights, telemetry measurements would allow monitoring of thermoregulation, muscular, and cardiac responses to weightlessness. In contrast, the five completed Cosmos/Bion flights, lacked the metabolic samples and behavioral task monitoring, but did facilitate studies of the neurovestibular system during several of the flights.


    Zugriff

    Zugriff über TIB

    Verfügbarkeit in meiner Bibliothek prüfen

    Bestellung bei Subito €


    Exportieren, teilen und zitieren



    Titel :

    Microgravity Flight - Accommodating Non-Human Primates


    Beteiligte:
    Dalton, Bonnie P. (Autor:in) / Searby, Nancy (Autor:in) / Ostrach, Louis (Autor:in)

    Kongress:

    Environmental Systems ; 1994 ; Friedrichshafen, Germany
    Space Environmental Control Systems ; 1994 ; Friedrichshafen, Germany


    Erscheinungsdatum :

    1994-01-01



    Medientyp :

    Aufsatz (Konferenz)


    Format :

    Keine Angabe


    Sprache :

    Englisch




    Microgravity Flight: Accommodating Non-Human Primates

    Dalton, Bonnie P. / Searby, Nancy / Ostrach, Louis | NTRS | 1995


    Microgravity Flight - Accommodating Non-Human Primates

    Dalton, Bonnie P. / Searby, Nancy / Ostrach, Louis | NTRS | 1994


    Microgravity Flight - Accommodating Non-Human Primates

    Dalton, Bonnie P. / Ostrach, Louis / Searby, Nancy | SAE Technical Papers | 1994


    Accommodating Rodents During Extended Microgravity Missions

    Eodice, Michael T. | SAE Technical Papers | 1997


    Failure-accommodating neural network flight control

    HUANG, CHIEN / TYLOCK, JAMES / ENGEL, STEVE et al. | AIAA | 1992