A new concept is introduced for assessing the risk of radiation-induced cancer to space travelers: a fluence-related risk coefficient F (called the risk cross section), which is the risk of a cancer per unit particle fluence for a given particle type. Fs are functions of the LET of the particles in the radiation field and, when integrated over fluence-LET spectra and summed, yield the risk of the endpoint of interest. As an example, tumor prevalence data in mice are used to estimate the probability of the induction of mouse Harderian-gland tumor per year on an extramagnetospheric mission inside an idealized shielding configuration of a spherical 1 g/sq cm hick aluminum shell. Results indicate a yearly tumor prevalence of 0.06 at solar minimum conditions, with 60 percent of this arising from charge components with Z between 10 and 28, and two-thirds of the contribution arising from LET components between 10 and 200 keV/micron.


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    Titel :

    Fluence-related risk coefficients using the Harderian gland data as an example


    Beteiligte:
    Curtis, S. B. (Autor:in) / Powers-Risius, P. (Autor:in) / Alpen, E. L. (Autor:in) / Townsend, L. W. (Autor:in) / Wilson, J. W. (Autor:in) / Fry, R. J. M. (Autor:in)

    Erschienen in:

    Erscheinungsdatum :

    1992-01-01



    Medientyp :

    Sonstige


    Format :

    Keine Angabe


    Sprache :

    Englisch


    Schlagwörter :


    Fluence-related risk coefficients using the Harderian gland data as an example

    Curtis, S.B. / Townsend, L.W. / Wilson, J.W. et al. | Elsevier | 1991





    Renault Fluence

    Perini,G. / Renault,FR | Kraftfahrwesen | 2004