Orthostatic intolerance is common in astronauts after prolonged space flight. However, the 'push-pull effect' in military aviators suggests that brief exposures to transitions between hypo- and hypergravity are sufficient to induce untoward autonomic cardiovascular physiology in susceptible individuals. We therefore investigated orthostatic tolerance and autonomic cardiovascular function in 16 healthy test subjects before and after a seated 2-hr parabolic flight. At the same time, we also investigated relationships between parabolic flight-induced vomiting and changes in orthostatic and autonomic cardiovascular function. After parabolic flight, 8 of 16 subjects could not tolerate a 30-min upright tilt test, compared to 2 of 16 before flight. Whereas new intolerance in non-Vomiters resembled the clinical postural tachycardia syndrome (POTS), new intolerance in Vomiters was characterized by comparatively isolated upright hypocapnia and cerebral vasoconstriction. As a group, Vomiters also had evidence for increased postflight fluctuations in efferent vagal-cardiac nerve traffic occurring independently of any superimposed change in respiration. Results suggest that syndromes of orthostatic intolerance resembling those occurring after space flight can occur after a brief (i.e., 2-hr) parabolic flight.


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    Titel :

    Orthostatic Intolerance and Motion Sickness After Parabolic Flight


    Beteiligte:
    T. T. Schlegel (Autor:in) / T. E. Brown (Autor:in) / S. J. Wood (Autor:in) / E. W. Benavides (Autor:in) / R. L. Bondar (Autor:in)

    Erscheinungsdatum :

    1999


    Format / Umfang :

    45 pages


    Medientyp :

    Report


    Format :

    Keine Angabe


    Sprache :

    Englisch




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    Predicting Motion Sickness During Parabolic Flight

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