Disclosed are the methods for treating kidney disease including autosomal dominant polycystic kidney disease (ADPKD) in a subject, comprising the step of administering to the subject a composition comprising a therapeutically effective amount of ticagrelor or a derivative thereof, treating ADPKD. Disclosed are methods of decreasing arginine vasopressin (AVP) production in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production. Disclosed are methods for treating dilutional hyponatremia in a subject comprising the step of administering to the subject a composition comprising an effective amount of ticagrelor, thereby decreasing AVP production.
TREATMENT OF KIDNEY DISEASES ASSOCIATED WITH ELEVATED AVP
2022-08-25
Patent
Elektronische Ressource
Englisch
IPC: | G08B SIGNALLING OR CALLING SYSTEMS , Signalisier- oder Rufsysteme / A61K Zubereitungen für medizinische, zahnärztliche oder kosmetische Zwecke , PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES / A61P SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS , Spezifische therapeutische Aktivität von chemischen Verbindungen oder medizinischen Zubereitungen / B64C AEROPLANES , Flugzeuge / H04N PICTORIAL COMMUNICATION, e.g. TELEVISION , Bildübertragung, z.B. Fernsehen |
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