AbstractChanges in trabecular bone composition during development of osteoporosis are used as a model for bone loss in microgravity conditions during a space flight. Symbolic dynamics and measures of complexity are proposed and applied to assess quantitatively the structural composition of bone tissue from 3D data sets of human tibia bone biopsies acquired by a micro-CT scanner. In order to justify the newly proposed approach, the measures of complexity of the bone architecture were compared with the results of traditional 2D bone histomorphometry. The proposed technique is able to quantify the structural loss of the bone tissue and may help to diagnose and to monitor changes in bone structure of patients on Earth as well as of the space-flying personnel.


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    Titel :

    Quantification of spatial structure of human proximal tibial bone biopsies using 3D measures of complexity


    Beteiligte:

    Erschienen in:

    Acta Astronautica ; 56 , 9-12 ; 820-830


    Erscheinungsdatum :

    2005-01-01


    Format / Umfang :

    11 pages




    Medientyp :

    Aufsatz (Zeitschrift)


    Format :

    Elektronische Ressource


    Sprache :

    Englisch




    Quantification of spatial structure of human proximal tibial bone biopsies using 3D measures of complexity

    Saparin, P. I. / Skovhus Thomsen, J. / Prohaska, S. et al. | British Library Conference Proceedings | 2005



    Quantification of spatial structure of human proximal tibial bone biopsies using 3D measures of complexity

    Saparin, P. I. / Skovhus Thomsen, J. / Prohaska, S. et al. | British Library Conference Proceedings | 2005


    Bone architecture assessment with measures of complexity

    Gowin, Wolfgang | Online Contents | 2001


    Bone architecture assessment with measures of complexity

    Gowin, W. / Saparin, P. / Kurths, J. et al. | British Library Conference Proceedings | 2001