Quantitative assessment of gait in patients with Parkinson's disease (PD) is an important step in addressing motor symptoms and improving clinical management. Based on the assessment of only 5 meters of gait with a single body-fixed-sensor placed on the lower back, this study presents a method for the identification of step-by-step kinematic parameters in 14 healthy controls and in 28 patients at early-to-moderate stages of idiopathic PD. Differences between groups in step-by-step kinematic parameters were evaluated to understand gait impairments in the PD group. Moreover, a discriminant model between groups was built from a subset of significant and independent parameters and based on a 10-fold cross-validated model. The discriminant model correctly classified a total of 89.5% participants with four kinematic parameters. The sensitivity of the model was 95.8% and the specificity 78.6%. The results indicate that the proposed method permitted to reasonably recognize idiopathic PD-associated gait from 5-m walking assessments. This motivates further investigation on the clinical utility of short episodes of gait assessment with body-fixed-sensors.


    Zugriff

    Download


    Exportieren, teilen und zitieren



    Titel :

    Is the Assessment of 5 Meters of Gait with a Single Body-Fixed-Sensor Enough to Recognize Idiopathic Parkinson's Disease-Associated Gait?


    Beteiligte:
    Micó-Amigo, M E (Autor:in) / Kingma, I (Autor:in) / Faber, G S (Autor:in) / Kunikoshi, A. (Autor:in) / van Uem, J. M T (Autor:in) / van Lummel, R C (Autor:in) / Maetzler, W. (Autor:in) / van Dieën, J H (Autor:in)

    Erscheinungsdatum :

    2017-05-01


    Anmerkungen:

    Micó-Amigo , M E , Kingma , I , Faber , G S , Kunikoshi , A , van Uem , J M T , van Lummel , R C , Maetzler , W & van Dieën , J H 2017 , ' Is the Assessment of 5 Meters of Gait with a Single Body-Fixed-Sensor Enough to Recognize Idiopathic Parkinson's Disease-Associated Gait? ' , Annals of Biomedical Engineering , vol. 45 , no. 5 , pp. 1266-1278 . https://doi.org/10.1007/s10439-017-1794-8



    Medientyp :

    Aufsatz (Zeitschrift)


    Format :

    Elektronische Ressource


    Sprache :

    Englisch



    Klassifikation :

    DDC:    629



    Measuring gait quality in parkinson’s disease through real-time gait phase recognition

    Mileti, Ilaria / Germanotta, Marco / Di Sipio, Enrica et al. | BASE | 2018

    Freier Zugriff

    A Single Wearable Sensor for Gait Analysis in Parkinson’s Disease: A Preliminary Study

    Pierleoni P. / Raggiunto S. / Belli A. et al. | BASE | 2022

    Freier Zugriff

    Sensor-based gait analysis in the premotor stage of LRRK2 G2019S-associated Parkinson's disease

    Sánchez Rodríguez, Antonio / Tirnauca, Cristina / Salas Gómez, Diana et al. | BASE | 2022

    Freier Zugriff


    Quantitative and qualitative gait assessments in Parkinson's disease patients

    Đurić-Jovičić, Milica D. / Jovičić, Nenad S. / Radovanović, Saša M. et al. | BASE | 2014

    Freier Zugriff